heptaminol indications/contra

Stem definitionDrug idCAS RN
1361 372-66-7

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • heptaminol
  • 2-Amino-6-hydroxy-6-methylheptane
  • heptaminol hydrochloride
  • heptaminol HCl
An amino alcohol that has been used as a myocardial stimulant and vasodilator and to relieve bronchospasm. Its most common therapeutic use is in orthostatic hypotension. The mechanism of heptaminol's therapeutic actions is not well understood although it has been suggested to affect catecholamine release or calcium metabolism.
  • Molecular weight: 145.25
  • Formula: C8H19NO
  • CLOGP: 0.48
  • LIPINSKI: 0
  • HAC: 2
  • HDO: 2
  • TPSA: 46.25
  • ALOGS: -0.95
  • ROTB: 4

Drug dosage:

DoseUnitRoute
0.45 g O
0.45 g P

Approvals:

None

FDA Adverse Event Reporting System

None

Pharmacologic Action:

scroll-->
SourceCodeDescription
ATC C01DX08 CARDIOVASCULAR SYSTEM
CARDIAC THERAPY
VASODILATORS USED IN CARDIAC DISEASES
Other vasodilators used in cardiac diseases

Drug Use (View source of the data)

None

Acid dissociation constants calculated using MoKa v3.0.0

scroll-->
Dissociation levelDissociation constantType (acidic/basic)
pKa1 10.61 Basic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

scroll-->
IDSource
CHEBI:94362 CHEBI
N0000166812 NUI
C0019223 UMLSCUI
D07158 KEGG_DRUG
3DQS188SY5 UNII
2030 INN_ID
5254 RXNORM
96259006 SNOMEDCT_US
N0000166812 NDFRT
005587 NDDF
006399 NDDF
D006535 MESH_DESCRIPTOR_UI
CHEMBL2107282 ChEMBL_ID
CHEMBL2111076 ChEMBL_ID
543-15-7 SECONDARY_CAS_RN
3590 PUBCHEM_CID

Pharmaceutical products:

None